Cloned (Comment) | Organism |
---|---|
a myc-His-tagged soluble version starting at amino acid position 155 (lacking the putative transmembrane region) expressed in 293F cells | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
immobilized metal ion affinity chromatography (Ni2+), anion-exchange chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
233000 mol L-leucine-7-amido-4-methyl coumarin/mol enzyme x min | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucine-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | L-leucine + 7-amino-4-methylcoumarin | - |
? | |
Leu-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu + H2O | - |
Homo sapiens | ? + Ile-Asn-Phe-Glu-Lys-Leu | - |
? | |
Leu-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu + H2O | - |
Homo sapiens | ? + Ile-Ile-Asn-Phe-Glu-Lys-Leu | - |
? | |
Leu-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu + H2O | trimming of further model epitope precursors to antigenic peptides are also tested | Homo sapiens | L-leucine + Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Placental leucine aminopeptidase | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 8 | almost 70% activity at pH 6.0, 50% activity at pH 8.0 | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | enzymatic properties to participate in generating or destroying MHC class I-presented peptides | Homo sapiens |