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Literature summary for 3.3.2.9 extracted from

  • Sevanian, A.; McLeod, L.L.
    Catalytic properties and inhibition of hepatic cholesterol-epoxide hydrolase (1986), J. Biol. Chem., 261, 54-59.
    View publication on PubMed
Search for more literature for 3.3.2.9

Inhibitors

Inhibitors Comment Organism Structure
cyclohexane oxide
-
 Rattus norvegicus
additional information no inhibition by isoquinoline, 7-oxocholesterol, 7-oxocholestanol, and 6-oxocholestanol Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with 5,6alpha-epoxy-5alpha-cholestan-3beta-ol and 5,6beta-epoxy-5alpha-cholestan-3beta-ol Rattus norvegicus ?
-
 ?
styrene epoxide + H2O
-
 Rattus norvegicus 1-phenyl-ethane-1,2-diol
-
 ?

Synonyms

Synonyms Comment Organism
styrene-epoxide hydrolase
-
 Rattus norvegicus
xenobiotic epoxide hydrolase
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0154
-
 cyclohexane oxide pH 7.4, 37°C Rattus norvegicus