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Literature summary for 3.3.2.9 extracted from

  • Liu, M.; Sun, A.; Shin, E.J.; Liu, X.; Kim, S.G.; Runyons, C.R.; Markesbery, W.; KIm, H.C.; Bing, G.
    Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin (2006), Eur. J. Neurosci., 23, 2027-2034.
    View publication on PubMed
Search for more literature for 3.3.2.9

Activating Compound

Activating Compound Comment Organism Structure
additional information enzyme expression is induced by exogenous beta-amyloid and trimethyl-tin, a neurotoxic agent, beta-amyloid aggregation induces enzyme expression in astrocytes Homo sapiens
additional information enzyme expression is induced by neurotoxic agent trimethyl-tin in hippocampus and entorhinal cortex Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens the enzyme is critical for biotransformations in xenobiotic metabolism and detoxification ?
-
 ?
additional information Rattus norvegicus the enzyme is critical for biotransformations in xenobiotic metabolism and detoxification ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 healthy humans and patients with Alzheimer's disease
-
Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte patchy distribution Homo sapiens
-
brain
-
 Homo sapiens
-
entorhinal area
-
 Rattus norvegicus
-
glial cell
-
 Homo sapiens
-
glial cell
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
hippocampus glial cell culture, enzyme expression is elevated in hippocampus and associated cortex of patients with Alzheimer's disease Homo sapiens
-
neuron pyramidal Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is critical for biotransformations in xenobiotic metabolism and detoxification Homo sapiens ?
-
 ?
additional information the enzyme is critical for biotransformations in xenobiotic metabolism and detoxification Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
mEH
-
 Homo sapiens
mEH
-
 Rattus norvegicus