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Literature summary for 3.3.2.9 extracted from
- Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities (1984), Carcinogenesis, 5, 7-9.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,1,1-trichloropropene oxide | - |
Oryctolagus cuniculus |  |
| 1,1,1-trichloropropene oxide | - |
Rattus norvegicus | |
| additional information | no inhibition by 5,6alpha-imino-5alpha-cholestane-3beta-ol | Oryctolagus cuniculus | |
| additional information | no inhibition by 5,6alpha-imino-5alpha-cholestane-3beta-ol | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
| microsome | - |
Oryctolagus cuniculus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
New Zealand white rabbits | - |
| Rattus norvegicus | - |
male Sprague-Dawley | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| preparation of liver microsomes, separation from the cholesterol 5,6-oxide hydrolase, EC 3.3.2.11, by immunoprecipitation | Rattus norvegicus |
| preparation of liver microsomes, separation from the cholesterol 5,6-oxide hydrolase, EC 3.3.2.11, by immunoprecipitation | Oryctolagus cuniculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme shows a broad substrate specificity, all epoxides with a trisubstituted oxirane ring are no or poor substrates, no activity with 5,6alpha-epoxy-5alpha-cholestan-3beta-ol | Rattus norvegicus | ? | - |
? | |
| additional information | the enzyme shows a broad substrate specificity, all epoxides with a trisubstituted oxirane ring are no or poor substrates, no activity with 5,6alpha-epoxy-5alpha-cholestan-3beta-ol | Oryctolagus cuniculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EHb | - |
Rattus norvegicus |
| EHb | - |
Oryctolagus cuniculus |
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Release 2023.1 (January 2023)
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