Any feedback?
Literature summary for 3.3.2.9 extracted from
- Endogenous role of microsomal epoxide hydrolase. Ontogenesis, induction inhibition, tissue distribution, immunological behaviour and purification of microsomal epoxide hydrolase with 16alpha,17alpha-epoxyandrostene-3-one as substrate (1982), Eur. J. Biochem., 126, 425-431.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| androstene oxide | inhibits hydration of estroxide and styrene 7,8-oxide | Rattus norvegicus |  |
| Cyclohexene oxide | inhibits hydration of estroxide, androstene oxide and styrene 7,8-oxide | Rattus norvegicus | |
| estroxide | inhibits hydration of androstene oxide and styrenen 7,8-oxide | Rattus norvegicus | |
| sodium cholate | inhibits hydration of estroxide and androstene oxide | Rattus norvegicus | |
| sodium deoxycholate | inhibits hydration of estroxide and androstene oxide | Rattus norvegicus | |
| styrene 7,8-oxide | inhibits hydration of estroxide and androstene oxide | Rattus norvegicus | |
| trans-stilbene oxide | inhibits hydration of estroxide, androstene oxide and styrene 7,8-oxide | Rattus norvegicus | |
| trichloropropene oxide | inhibits hydration of estroxide, androstene oxide and styrene 7,8-oxide | Rattus norvegicus | |
| Tween-80 | inhibits hydration of estroxide and androstene oxide | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | no activity detected | Rattus norvegicus | 5829 | - |
| microsome | - |
Rattus norvegicus | - |
- |
| mitochondrion | very low activity | Rattus norvegicus | 5739 | - |
| rough endoplasmic reticulum | - |
Rattus norvegicus | 5791 | - |
| smooth endoplasmic reticulum | - |
Rattus norvegicus | 5790 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal gland | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| lung | - |
Rattus norvegicus | - |
| ovary | - |
Rattus norvegicus | - |
| testis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| androstene oxide + H2O | - |
Rattus norvegicus | ? | - |
? | |
| benzopyrene 4,5-oxide + H2O | - |
Rattus norvegicus | (-)benzopyrene 4,5-dihydrodiol | - |
? | |
| estroxide + H2O | 16alpha,17alpha-epoxyestratrienol | Rattus norvegicus | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
