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Literature summary for 3.3.2.10 extracted from

  • Zhang, W.; Davis, C.M.; Edin, M.L.; Lee, C.R.; Zeldin, D.C.; Alkayed, N.J.
    Role of endothelial soluble epoxide hydrolase in cerebrovascular function and ischemic injury (2013), PLoS ONE, 8, e61244.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Mus musculus Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelium
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
SEH
-
Homo sapiens

General Information

General Information Comment Organism
physiological function transgenic enzyme expression in endothelium results in impaired endothelium-dependent vasodilation in the cerebral circulation. Females are more susceptible to enhanced ischemic damage as a result of increased endothelial soluble epoxide hydrolase than males, especially in end-arteriolar striatal region Homo sapiens