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Literature summary for 3.3.2.10 extracted from
- Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy (2015), Brain Behav. Immun., 43, 118-129.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 12-(3-adamantan-1-yl-ureido)-dodecanoic acid | - |
Mus musculus |  |
| N-[1-(1-oxopropyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea | - |
Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Mus musculus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| astrocyte | - |
Mus musculus | - |
| dentate gyrus | - |
Mus musculus | - |
| hippocampus | - |
Mus musculus | - |
| microglia | - |
Mus musculus | - |
| neuron | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SEH | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | enzyme expression increases 3-28 days after pilocarpine-induced status epilepticus | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme knockout mice are more susceptible to seizures than wild type mice | Mus musculus |
| physiological function | the enzyme plays an important role in the generation of epilepsy | Mus musculus |
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Release 2023.1 (January 2023)
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