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Literature summary for 3.3.2.10 extracted from

  • Falck, J.; Kodela, R.; Manne, R.; Atcha, K.; Puli, N.; Dubasi, N.; Manthati, V.; Capdevila, J.; Yi, X.; Goldman, D.; Morisseau, C.; Hammock, B.; Campbell, W.
    14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: Influence upon vascular relaxation and soluble epoxide hydrolase inhibition (2009), J. Med. Chem., 52, 5069-5075.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.3.2.10

Inhibitors

Inhibitors Comment Organism Structure
(4Z)-9-[(pentylcarbamoyl)amino]non-4-enoic acid
-
 Bos taurus
(4Z)-9-[(pentylcarbamoyl)amino]non-4-enoic acid
-
 Homo sapiens
(5Z)-13-[(pentylcarbamoyl)amino]tridec-5-enoic acid
-
 Bos taurus
(5Z)-13-[(pentylcarbamoyl)amino]tridec-5-enoic acid
-
 Homo sapiens
(8E)-13-[(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8E)-13-[(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-12-[(hexylcarbamoyl)amino]dodec-8-enoic acid
-
 Bos taurus
(8Z)-12-[(hexylcarbamoyl)amino]dodec-8-enoic acid
-
 Homo sapiens
(8Z)-12-[[(pentylcarbamoyl)amino]oxy]dodec-8-enoic acid
-
 Bos taurus
(8Z)-12-[[(pentylcarbamoyl)amino]oxy]dodec-8-enoic acid
-
 Homo sapiens
(8Z)-13-(4-pentyl-1H-1,2,3-triazol-1-yl)tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-(4-pentyl-1H-1,2,3-triazol-1-yl)tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-(5-pentyl-4,5-dihydro-1,3-oxazol-2-yl)tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-(5-pentyl-4,5-dihydro-1,3-oxazol-2-yl)tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-(5-pentylfuran-2-yl)tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-(5-pentylfuran-2-yl)tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-(heptanoylamino)tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-(heptanoylamino)tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[(pentylcarbamothioyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[(pentylcarbamothioyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[(pentylcarbamoyl)oxy]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[(pentylcarbamoyl)oxy]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[heptanoyl(methyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[heptanoyl(methyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[heptanoyl(propan-2-yl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[heptanoyl(propan-2-yl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[methyl(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[methyl(pentylcarbamoyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[methyl[methyl(pentyl)carbamoyl]amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[methyl[methyl(pentyl)carbamoyl]amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[[(butylamino)(oxo)acetyl]amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[[(butylamino)(oxo)acetyl]amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[[(pentyloxy)carbonyl]amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[[(pentyloxy)carbonyl]amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[[methyl(pentyl)carbamoyl]amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[[methyl(pentyl)carbamoyl]amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-13-[[[butyl(methyl)amino](oxo)acetyl](methyl)amino]tridec-8-enoic acid
-
 Bos taurus
(8Z)-13-[[[butyl(methyl)amino](oxo)acetyl](methyl)amino]tridec-8-enoic acid
-
 Homo sapiens
(8Z)-14-(hexylamino)-14-oxotetradec-8-enoic acid
-
 Bos taurus
(8Z)-14-(hexylamino)-14-oxotetradec-8-enoic acid
-
 Homo sapiens
(8Z)-14-[(butylcarbamoyl)amino]tetradec-8-enoic acid
-
 Bos taurus
(8Z)-14-[(butylcarbamoyl)amino]tetradec-8-enoic acid
-
 Homo sapiens
(8Z)-14-[hexyl(methyl)amino]-14-oxotetradec-8-enoic acid
-
 Bos taurus
(8Z)-14-[hexyl(methyl)amino]-14-oxotetradec-8-enoic acid
-
 Homo sapiens
(8Z,11Z)-16-[(ethylcarbamoyl)amino]hexadeca-8,11-dienoic acid
-
 Bos taurus
(8Z,11Z)-16-[(ethylcarbamoyl)amino]hexadeca-8,11-dienoic acid
-
 Homo sapiens
13-(heptanoylamino)tridec-5-ynoic acid
-
 Bos taurus
13-(heptanoylamino)tridec-5-ynoic acid
-
 Homo sapiens
13-[(pentylcarbamoyl)amino]tridec-8-ynoic acid
-
 Bos taurus
13-[(pentylcarbamoyl)amino]tridec-8-ynoic acid
-
 Homo sapiens
13-[methyl[methyl(pentyl)carbamoyl]amino]tridec-5-ynoic acid
-
 Bos taurus
13-[methyl[methyl(pentyl)carbamoyl]amino]tridec-5-ynoic acid
-
 Homo sapiens
9-[(pentylcarbamoyl)amino]non-4-ynoic acid
-
 Bos taurus
9-[(pentylcarbamoyl)amino]non-4-ynoic acid
-
 Homo sapiens
additional information inhibitor screening and structure-function analysis, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Bos taurus
-
-
soluble
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens P34913
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation recombinant enzyme Homo sapiens
-
coronary artery
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O enzyme-substrate binding, overview Bos taurus (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
(5Z,8Z,11Z)-14,15-epoxyeicosatrienoic acid + H2O enzyme-substrate binding, overview Homo sapiens (5Z,8Z,11Z)-14,15-dihydroxyeicosatrienoic acid
-
 ?
cyano(2-methoxynaphthalen-6-yl)methyl trans-(3-phenyl-oxiran-2-yl)methyl carbonate + H2O a fluorogenic substrate Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
SEH
-
 Bos taurus
SEH
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Homo sapiens