Application | Comment | Organism |
---|---|---|
medicine | allelic variation of EPHX2 is associated with heart failure | Mus musculus |
medicine | allelic variation of EPHX2 is associated with heart failure | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-adamantan-1-yl-3-(5-(2-(2-ethoxyethoxy)ethoxy)pentyl)urea | - |
Mus musculus | |
1-adamantan-1-yl-3-(5-(2-(2-ethoxyethoxy)ethoxy)pentyl)urea | - |
Rattus norvegicus | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl ester | selective soluble epoxide hydrolase inhibitor | Mus musculus | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl ester | selective soluble epoxide hydrolase inhibitor | Rattus norvegicus | |
12-(3-adamantan-1-yl-ureido)dodecanoic acid | selective soluble epoxide hydrolase inhibitor | Mus musculus | |
12-(3-adamantan-1-yl-ureido)dodecanoic acid | selective soluble epoxide hydrolase inhibitor | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Mus musculus | - |
heart | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5Z,8Z,11Z)-14,15-epoxyeicosa-5,8,11-trienoic acid + H2O | i.e. 14,15-EET | Mus musculus | (5Z,8Z,11Z)-14,15-dihydroxyeicosa-5,8,11-trienoic acid | i.e. 14,15-DHET | ? | |
(5Z,8Z,11Z)-14,15-epoxyeicosa-5,8,11-trienoic acid + H2O | i.e. 14,15-EET | Rattus norvegicus | (5Z,8Z,11Z)-14,15-dihydroxyeicosa-5,8,11-trienoic acid | i.e. 14,15-DHET | ? |
Synonyms | Comment | Organism |
---|---|---|
EPHX2 | - |
Mus musculus |
EPHX2 | - |
Rattus norvegicus |
SEH | - |
Mus musculus |
SEH | - |
Rattus norvegicus |