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Literature summary for 3.3.2.1 extracted from
- Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a (2007), Biochem. Biophys. Res. Commun., 361, 287-293.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| ISOC2 cDNA is cloned into the pECFP and pCMV-HA vector | Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 23000 | - |
determinated by Western blot analysis | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| isochorismate + H2O | Mus musculus | - |
2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate | - |
? |  |
| isochorismate + H2O | Homo sapiens | - |
2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293T cell | - |
Homo sapiens | - |
| liver | a yeast two-hybrid assay is performed to screen the proteins interacting with p16INK4a in pretransformed human liver cDNA library, ISOC2 is identified as an interacting protein | Homo sapiens | - |
| stomach | - |
Mus musculus | - |
| urinary tract | - |
Mus musculus | - |
| uterus | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| isochorismate + H2O | - |
Mus musculus | 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate | - |
? | |
| isochorismate + H2O | - |
Homo sapiens | 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ISOC2 | - |
Mus musculus |
| ISOC2 | - |
Homo sapiens |
| isochorismatase | - |
Mus musculus |
| isochorismatase | - |
Homo sapiens |
| isochorismatase domain containing 2 | - |
Mus musculus |
| isochorismatase domain containing 2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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