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Literature summary for 3.2.2.9 extracted from

  • Buerstenbinder, K.; Waduwara, I.; Schoor, S.; Moffatt, B.A.; Wirtz, M.; Minocha, S.C.; Oppermann, Y.; Bouchereau, A.; Hell, R.; Sauter, M.
    Inhibition of 5'-methylthioadenosine metabolism in the Yang cycle alters polyamine levels, and impairs seedling growth and reproduction in Arabidopsis (2010), Plant J., 62, 977-988.
    View publication on PubMed
Search for more literature for 3.2.2.9

Activating Compound

Activating Compound Comment Organism Structure
5'-methylthioadenosine enzyme activity is induced by 5'-methylthioadenosine Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Arabidopsis thaliana

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
28000
-
 x * 28000, SDS-PAGE Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-methylthioadenosine + H2O Arabidopsis thaliana
-
 5-methylthio-D-ribose + adenine
-
 ?
S-adenosyl-L-homocysteine + H2O Arabidopsis thaliana
-
 S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Columbia
-

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-methylthioadenosine + H2O
-
 Arabidopsis thaliana 5-methylthio-D-ribose + adenine
-
 ?
S-adenosyl-L-homocysteine + H2O
-
 Arabidopsis thaliana S-(5-deoxy-D-ribos-5-yl)-L-homocysteine + adenine
-
 ?

Subunits

Subunits Comment Organism
? x * 28000, SDS-PAGE Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
MTA nucleosidase
-
 Arabidopsis thaliana
MTN1 isoform, provides approximately 80% of the total 5'-methylthioadenosine nucleosidase activity Arabidopsis thaliana
MTN2 isoform Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction single MTN1 or MTN2 knock down mutants do not display an obvious morphological phenotype when grown on sulfur sufficient media or on soil, mtn1-1/mtn2-1 double mutant plants display delayed flowering, produce underdeveloped siliques, and are sterile Arabidopsis thaliana
physiological function 5'-methylthioadenosine nucleosidase is a crucial enzyme of the Yang cycle Arabidopsis thaliana