Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P28907 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HUVEC cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CD38 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | no induction of CD38 mRNA by senescence itself. Cytokines and chemokines expressed by senescent cells induce CD38 expression in macrophages | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | senescent cells do not have high expression of CD38. The senescent associated secretory phenotype factors secreted by senescent cells induce CD38 mRNA and protein expression and increase CD38-NADase activity in non-senescent cells such as endothelial cells or bone marrow derived macrophages | Homo sapiens |