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Literature summary for 3.2.2.5 extracted from
- Snake venom NAD glycohydrolase: purification, immobilization, and transglycosidation (1986), Methods Enzymol., 122, 173-181.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Bungarus fasciatus |  |
| ADPribose | - |
Bungarus fasciatus | |
| AMP | - |
Bungarus fasciatus | |
| additional information | variety of pyridine bases, pyridine nucleotides | Bungarus fasciatus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.014 | - |
NAD+ | - |
Bungarus fasciatus | |
| 1.4 | - |
Pyridine | - |
Bungarus fasciatus | |
| 3.2 | - |
3-aminopyridine | - |
Bungarus fasciatus | |
| 6.1 | - |
3-pyridylacetonitrile | - |
Bungarus fasciatus | |
| 6.5 | - |
3-methylpyridine | - |
Bungarus fasciatus | |
| 7.9 | - |
3-Pyridylcarbinol | - |
Bungarus fasciatus | |
| 20 | - |
3-acetylpyridine | - |
Bungarus fasciatus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 62000 | - |
2 * 62000, SDS-PAGE | Bungarus fasciatus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + H2O | Bungarus fasciatus | - |
ADPribose + nicotinamide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bungarus fasciatus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bungarus fasciatus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Bungarus fasciatus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1320 | - |
- |
Bungarus fasciatus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-acetylpyridine + H2O | - |
Bungarus fasciatus | ? | - |
? | |
| 3-aminopyridine + H2O | - |
Bungarus fasciatus | ? | - |
? | |
| 3-methylpyridine + H2O | - |
Bungarus fasciatus | ? | - |
? | |
| 3-pyridylacetonitrile + H2O | - |
Bungarus fasciatus | ? | - |
? | |
| 3-pyridylcarbinol + H2O | - |
Bungarus fasciatus | ? | - |
? | |
| additional information | alcoholysis of NAD to form O-alkyl-ADP-ribosides, ADP-ribosylation of imidazole derivates | Bungarus fasciatus | ? | - |
? | |
| NAD+ + H2O | - |
Bungarus fasciatus | ADPribose + nicotinamide | - |
? | |
| pyridine + H2O | - |
Bungarus fasciatus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 62000, SDS-PAGE | Bungarus fasciatus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Bungarus fasciatus |
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