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Literature summary for 3.2.2.3 extracted from

  • Baccolini, C.; Witte, C.P.
    AMP and GMP catabolism in Arabidopsis converge on xanthosine, which is degraded by a nucleoside hydrolase heterocomplex (2019), Plant Cell, 31, 734-751 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SJM7
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Synonyms

Synonyms Comment Organism
NSH1
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Arabidopsis thaliana
nucleoside hydrolase 1
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Arabidopsis thaliana
URH1
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function nucleoside hydrolase NSH1 activates NSH2 in vitro and in vivo, forming a complex with almost two orders of magnitude higher catalytic efficiency for xanthosine hydrolysis than observed for NSH1 alone. An inactive NSH1 point mutant can activate NSH2 in vivo, fully preventing purine nucleoside accumulation in Nsh1 mutant background Arabidopsis thaliana