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Literature summary for 3.2.2.27 extracted from

  • Esadze, A.; Rodriguez, G.; Weiser, B.P.; Cole, P.A.; Stivers, J.T.
    Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells (2017), Nucleic Acids Res., 45, 12413-12424 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.27

Inhibitors

Inhibitors Comment Organism Structure
Ugi protein
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HAP-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
uracil-containing DNA + H2O uracil-containing DNA substrates with two uracil sites spaced 10, 40 or 80 bp apart Homo sapiens uracil + DNA with abasic site
-
 ?

Synonyms

Synonyms Comment Organism
UNG2 isoform Homo sapiens
uracil DNA glycosylase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function the DNA repair enzyme excises uracil from U/A and U/G base pairs and initiates the process of uracil base excision repair Homo sapiens