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Literature summary for 3.2.2.27 extracted from

  • Schormann, N.; Banerjee, S.; Ricciardi, R.; Chattopadhyay, D.
    Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA glycosylase (2015), BMC Struct. Biol., 15, 10 .
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with an undamaged double stranded DNA, hanging drop vapor diffusion method, using 16 % PEG6K, 0.08 M Tris buffer, pH 8.5, and 20% (v/v) glycerol Vaccinia virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
uracil-containing single-stranded DNA + H2O Vaccinia virus
-
uracil + single-stranded DNA with abasic site
-
?
uracil-mismatched double-stranded DNA + H2O Vaccinia virus
-
uracil + double-stranded DNA with abasic site
-
?

Organism

Organism UniProt Comment Textmining
Vaccinia virus P04303
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Vaccinia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
uracil-containing single-stranded DNA + H2O
-
Vaccinia virus uracil + single-stranded DNA with abasic site
-
?
uracil-mismatched double-stranded DNA + H2O
-
Vaccinia virus uracil + double-stranded DNA with abasic site
-
?

Synonyms

Synonyms Comment Organism
UDG
-
Vaccinia virus
UNG
-
Vaccinia virus