Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ugi peptide | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
uracil-mismatched DNA + H2O | Homo sapiens | - |
uracil + DNA with abasic site | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
uracil-mismatched DNA + H2O | - |
Homo sapiens | uracil + DNA with abasic site | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UNG | - |
Homo sapiens |
uracil DNA glycosylase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme inhibition enhances APOBEC3G-induced hypermutation of hepatitis B virus nucleocapsid-associated DNA | Homo sapiens |
physiological function | uracil DNA glycosylase is a base excision repair enzyme that removes uracil residues from DNA following dUTP misincorporations or cytosine deaminations. The enzyme is also essential for class-switch recombination and somatic hypermutation | Homo sapiens |