Literature summary for 3.2.2.27 extracted from

Hegre, S.A.; Saetrom, P.; Aas, P.A.; Pettersen, H.S.; Otterlei, M.; Krokan, H.E.
Multiple microRNAs may regulate the DNA repair enzyme uracil-DNA glycosylase (2013), DNA Repair, 12, 80-86.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
uracil-mismatched single-stranded DNA + H2O	Homo sapiens	-	uracil + single-stranded DNA with abasic site	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
uracil-mismatched single-stranded DNA + H2O	-	Homo sapiens	uracil + single-stranded DNA with abasic site	-	?

Synonyms

Synonyms	Comment	Organism
UNG2	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	protein and mRNA levels rapidly decline in G2/M phase. Micro-RNAs down-regulate enzyme activity, mRNA, and protein levels by directly targeting the conserved seed sites in the 3'-untranslated region	down

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Release 2023.1 (January 2023)