Crystallization (Comment) | Organism |
---|---|
structures of zinc- and cobalt-associated enzyme | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | zinc(II)- and cobalt(II)-associated enzyme, metal-binding domain | Escherichia coli | |
Zn2+ | zinc(II)- and cobalt(II)-associated enzyme, metal-binding domain, zinc-associated motif is located at the C-terminus and essential for damaged DNA recognition | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | Escherichia coli | plays an important role in base excision repair of oxidatively damaged DNA | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA + H2O | plays an important role in base excision repair of oxidatively damaged DNA | Escherichia coli | ? | - |
? | |
DNA containing 8-hydroxyguanine residues + H2O | 7,8-dihydro-8-oxoguanine-DNA | Escherichia coli | 8-hydroxyguanine + DNA | - |
? | |
DNA containing 8-hydroxyguanine residues + H2O | 54 nt DNA oligomer, CoFpg and ZnFpg are equally active at cleaving the DNA at the site of the oxidized guanine | Escherichia coli | 8-hydroxyguanine + DNA | - |
? |