Application | Comment | Organism |
---|---|---|
diagnostics | identification of highly toxic Escherichia coli variants in humans, animals, and food by using primer homologous to the elastase recognition site of Stx2dact or other variants | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
additional information | elastase increases cytotoxicity of Shiga toxin type 2 by cleaving 2 amino acids of toxin subunit A rendering it more toxic | Escherichia coli |
additional information | P1130 and stx1 deletion mutants of CVM9322, CVM9557, and CVM9584 show 13-30-fold increased Vero cell cytotoxicities after treatment with porcine pancreatic elastase | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | Q8KTU8 | Shiga toxin 2A subunit; STEC (Shiga toxin producing Escherichia coli) isolates from cows, meat, human | - |
Synonyms | Comment | Organism |
---|---|---|
Shiga toxin | variant Stx2dact (mucus-activatable Shiga toxin type 2), elastase cleaves 2 amino acids of toxin subunit A rendering it more toxic | Escherichia coli |
Shiga toxin type 2 | - |
Escherichia coli |
Stx2 | - |
Escherichia coli |
Stx2dact | variant of Shiga toxin type 2 | Escherichia coli |