Cloned (Comment) | Organism |
---|---|
expression in Saccharomyces cerevisiae strain mak8-1 which is more resistant to the enzyme in vivo due to higher affinity for aminoacyl-tRNA | Phytolacca americana |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
puromycin | prior incubation of ribosomes with puromycin inhibits both the binding and depurination by the enzyme | Phytolacca americana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Phytolacca americana | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
25S rNA + H2O | - |
Phytolacca americana | ? | enzyme depurinates the sarcin/ricin loop when the A-site of the ribosomal peptidyl-transferase center is unoccupied | ? |