Application | Comment | Organism |
---|---|---|
medicine | disruption of vascular leak syndrome-inducing site and of ribotoxic site. Injection i.m. into mice protects them against a ricin challenge of 10 LD50s. Injection into humans shows that the mutant is safe and elicits ricin-neutralizing antibodies in five of five individuals in the high-dose group | Ricinus communis |
Protein Variants | Comment | Organism |
---|---|---|
V76M/Y80A | disruption of vascular leak syndrome-inducing site and of ribotoxic site. Injection i.m. into mice protects them against a ricin challenge of 10 LD50s. Injection into humans shows that the mutant is safe and elicits ricin-neutralizing antibodies in five of five individuals in the high-dose group | Ricinus communis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Ricinus communis | - |
- |
- |