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Literature summary for 3.2.2.22 extracted from

  • Mantis, N.J.; McGuinness, C.R.; Sonuyi, O.; Edwards, G.; Farrant, S.A.
    Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication (2006), Infect. Immun., 74, 3455-3462.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine isolation of monoclonal IgA antibodies active against ricin A chain or ricin B chain, respectively, that neutralize ricin in a Vero cell cytotoxicity assay, block toxin-induced interleukin-8 release by the human macrophage cell line 28SC, and protect polarized epithelial cell monolayers from ricin-mediated protein synthesis inhibition Ricinus communis

Organism

Organism UniProt Comment Textmining
Ricinus communis
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