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Literature summary for 3.2.2.22 extracted from
- TYchi, a novel chitinase with RNA N-glycosidase and anti-tumor activities (2008), Front. Biosci., 13, 3127-3135.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Trichosanthes kirilowii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trichosanthes kirilowii | - |
isoform Tychi, expression is induced by infection with Fusarium oxysporum. Enzyme exhibits RNA N-glycosidase and chitin hydrolase activities | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | in a cell-free rabbit reticulocyte lysate system, enzyme inhibits protein synthesis with an IC50 of about 5 nM. Enzyme is cytotoxic to leukemia U937 and choriocarcinoma JAR cells | Trichosanthes kirilowii | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TYchi | - |
Trichosanthes kirilowii |
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Release 2023.1 (January 2023)
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