Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.2.22 extracted from

  • Wang, M.; Hudak, K.A.
    A novel interaction of pokeweed antiviral protein with translation initiation factors 4G and iso4G: a potential indirect mechanism to access viral RNAs (2006), Nucleic Acids Res., 34, 1174-1181.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Phytolacca americana the enzyme is active on viral RNA, e.g. from Human immunodeficiency virus-1 and Brome mosaic virus, RNA accession mechanism via interaction with translation initiation factors 4G and iso4G, overview ?
-
?
rRNA + H2O Phytolacca americana depurination of the sarcin-ricin loop of eukaryotic large rRNA ?
-
?

Organism

Organism UniProt Comment Textmining
Phytolacca americana
-
pokeweed
-

Purification (Commentary)

Purification (Comment) Organism
by affinity chromatography on a m7G-resin Phytolacca americana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme interacts with translation initiation factors 4G and iso4G, binding and interaction study with wild-type and mutant factors, overview, PAP binds to thr m7G cap structure Phytolacca americana ?
-
?
RNA + H2O the enzyme is active on viral RNA, e.g. from Human immunodeficiency virus-1 and Brome mosaic virus, RNA accession mechanism via interaction with translation initiation factors 4G and iso4G, overview Phytolacca americana ?
-
?
RNA + H2O the enzyme is active on viral RNA, e.g. from Human immunodeficiency virus-1 and Brome mosaic virus Phytolacca americana ?
-
?
rRNA + H2O depurination of the sarcin-ricin loop of eukaryotic large rRNA Phytolacca americana ?
-
?

Synonyms

Synonyms Comment Organism
PAP
-
Phytolacca americana
pokeweed anti-viral protein
-
Phytolacca americana
type I ribosome-inactivating protein
-
Phytolacca americana