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Literature summary for 3.2.2.21 extracted from
- Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates (2012), J. Am. Chem. Soc., 134, 9622-9633.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | Escherichia coli | - |
7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA | 7-methylguanine is cleaved the most quickly | ? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P04395 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alkylated DNA + H2O | - |
Escherichia coli | 7-methyladenine + 7-methylguanine + 3-methyladenine + 3-methylguanine + purine + 6-chloropurine + xanthine + DNA | 7-methylguanine is cleaved the most quickly | ? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-methyladenine DANN glycosylase II | - |
Escherichia coli |
| AlkA | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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