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Literature summary for 3.2.2.19 extracted from
- Immunohistochemical localization of ADP-ribosylarginine hydrolase in rodent CNS (1997), Brain Res., 746, 1-9.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | - |
Mus musculus |  |
| dithiothreitol | - |
Rattus norvegicus | |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression as a glutathione S-transferase-linked fusion protein in Escherichia coli | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | brain cytosol | Rattus norvegicus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Mus musculus | |
| Mg2+ | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 38000 | - |
- |
Mus musculus |
| 38000 | - |
- |
Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP-ribose-arginine + H2O | Rhodospirillum rubrum | in nitrogen fixing bacteria, Rhodospirillium rubrum, ADP-ribosylation-de-ADP-ribosylation of a specific arginine-residue of dinitrogenase reductase has been shown to regulate the enzyme activity | ADP-ribose + arginine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Rhodospirillum rubrum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| brain | hypothalamus | Mus musculus | - |
| brain | pyramidal cells of the cerebral cortex | Mus musculus | - |
| brain | pyramidal cells of the hippocampus | Mus musculus | - |
| brain | dorsal thalamus | Mus musculus | - |
| brain | purkinje cells and deep nuclei of the cerebellum | Mus musculus | - |
| brain | red nucleus, Darkschewitsch nucleus and medial parabrachial nucleus of the lower brainstem | Mus musculus | - |
| brain | amygdala | Mus musculus | - |
| brain | caudate-putamen and claustrum of the basal ganglia | Mus musculus | - |
| brain | ependymal cells | Mus musculus | - |
| brain | medial habenular nucleus and lateral habenular nucleus of the habenula | Mus musculus | - |
| cerebrospinal fluid | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.00183 | - |
as a GST-fusion protein in cerebrospinal fluid | Rattus norvegicus |
| 0.00815 | - |
as a GST-fusion protein in brain cytosol | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP-ribose-arginine + H2O | in nitrogen fixing bacteria, Rhodospirillium rubrum, ADP-ribosylation-de-ADP-ribosylation of a specific arginine-residue of dinitrogenase reductase has been shown to regulate the enzyme activity | Rhodospirillum rubrum | ADP-ribose + arginine | - |
? | |
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Release 2023.1 (January 2023)
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