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Literature summary for 3.2.2.17 extracted from

  • Hacker, E.; Muller, H.K.; Hayward, N.; Fahey, P.; Walker, G.
    Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR (2010), Pigment Cell Melanoma Res., 23, 121-128.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information treatment of Cdk4(R24C/R24C)/Nras(Q61K) mice topically with the T4 endonuclease V DNA repair enzyme immediately prior to neonatal ultraviolet radiation (UVR) exposure has a powerful effect in exacerbating melanoma development, overview Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Tequatrovirus T4 the enzyme reduces the incidence of basal-cell and squamous cell carcinoma in mice. Treatment of Cdk4(R24C/R24C)/Nras(Q61K) mice topically with the T4 endonuclease V DNA repair enzyme immediately prior to neonatal ultraviolet radiation (UVR) exposure has a powerful effect in exacerbating melanoma development, overview ?
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Organism

Organism UniProt Comment Textmining
Tequatrovirus T4
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme reduces the incidence of basal-cell and squamous cell carcinoma in mice. Treatment of Cdk4(R24C/R24C)/Nras(Q61K) mice topically with the T4 endonuclease V DNA repair enzyme immediately prior to neonatal ultraviolet radiation (UVR) exposure has a powerful effect in exacerbating melanoma development, overview Tequatrovirus T4 ?
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?

Synonyms

Synonyms Comment Organism
dimericine
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Tequatrovirus T4
T4 endonuclease V
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Tequatrovirus T4
T4 endonuclease V DNA repair enzyme
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Tequatrovirus T4