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Literature summary for 3.2.2.16 extracted from

  • Bao, Y.; Zhang, X.; Jiang, Q.; Xue, T.; Sun, B.
    Pfs promotes autolysis-dependent release of eDNA and biofilm formation in Staphylococcus aureus (2015), Med. Microbiol. Immunol., 204, 215-226.
    View publication on PubMed
Search for more literature for 3.2.2.16

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-methyl-5'-thioadenosine + H2O Staphylococcus aureus
-
 S-methyl-5-thio-D-ribose + adenine
-
 ?
S-methyl-5'-thioadenosine + H2O Staphylococcus aureus NCTC 8325
-
 S-methyl-5-thio-D-ribose + adenine
-
 ?

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
-
-
Staphylococcus aureus NCTC 8325
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-methyl-5'-thioadenosine + H2O
-
 Staphylococcus aureus S-methyl-5-thio-D-ribose + adenine
-
 ?
S-methyl-5'-thioadenosine + H2O
-
 Staphylococcus aureus NCTC 8325 S-methyl-5-thio-D-ribose + adenine
-
 ?

Synonyms

Synonyms Comment Organism
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
-
 Staphylococcus aureus
Pfs
-
 Staphylococcus aureus

General Information

General Information Comment Organism
malfunction the deletion of the enzyme gene reduces bacterial clumping ability and results in the decreased biofilm formation. The gene mutation also significantly decreases the amount of eDNA present in the biofilm and the cell autolysis Staphylococcus aureus
physiological function the enzyme promotes autolysis-dependent release of eDNA and biofilm formation Staphylococcus aureus