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Literature summary for 3.2.2.16 extracted from
- Transition-state analysis of S. pneumoniae 5-methylthioadenosine nucleosidase (2007), J. Am. Chem. Soc., 129, 2783-2795.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptococcus pneumoniae | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| S-methyl-5'-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine | SN1 transition state with no covalent participation of the adenine or the water nucleophile. Isotope effects predict a 3-endo conformation for the ribosyl oxacarbenium-ion transition state. The N7 of the leaving group adenine is not protonated in the transition state | Streptococcus pneumoniae |
aSynonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MTAN | - |
Streptococcus pneumoniae |
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