Any feedback?
Literature summary for 3.2.2.16 extracted from
- Kinetic properties of fluorinated substrate analogues on 5'-methylthioadenosine nucleosidase from Escherichia coli (1996), Eur. J. Med. Chem., 31, 37-41.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | potential chemotherapeutic agent | Escherichia coli |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0005 | - |
5'-methylthioadenosine | - |
Escherichia coli |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5'-methylthioadenosine + H2O | Escherichia coli | - |
? | - |
? | |
| 5'-methylthioadenosine + H2O | Escherichia coli B / ATCC 11303 | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
B | - |
| Escherichia coli B / ATCC 11303 | - |
B | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5'-deoxy-5'-(difluoromethylthio)adenosine + H2O | DFMTA, fluorinated substrate analogue | Escherichia coli | 5-deoxy-5-(difluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-deoxy-5'-(difluoromethylthio)adenosine + H2O | DFMTA, fluorinated substrate analogue | Escherichia coli B / ATCC 11303 | 5-deoxy-5-(difluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-deoxy-5'-(monofluoromethylthio)adenosine + H2O | MFMTA , fluorinated analogue of MTA | Escherichia coli | 5-deoxy-5-(monofluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-deoxy-5'-(monofluoromethylthio)adenosine + H2O | MFMTA , fluorinated analogue of MTA | Escherichia coli B / ATCC 11303 | 5-deoxy-5-(monofluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-deoxy-5'-(trifluoromethylthio)adenosine + H2O | TFMTA, fluorinated substrate analogue | Escherichia coli | 5-deoxy-5-(trifluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-deoxy-5'-(trifluoromethylthio)adenosine + H2O | TFMTA, fluorinated substrate analogue | Escherichia coli B / ATCC 11303 | 5-deoxy-5-(trifluoromethylthio)-D-ribose + adenine | - |
? | |
| 5'-methylthioadenosine + H2O | - |
Escherichia coli | ? | - |
? | |
| 5'-methylthioadenosine + H2O | - |
Escherichia coli B / ATCC 11303 | ? | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
