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Literature summary for 3.2.2.16 extracted from

  • Guranowski, A.B.; Chiang, P.K.; Cantoni, G.L.
    5'-Methylthioadenosine nucleosidase(Lupinus luteus seeds) (1983), Methods Enzymol., 94, 365-369.
No PubMed abstract available
Search for more literature for 3.2.2.16

Inhibitors

Inhibitors Comment Organism Structure
(S)-9-(2,3-dihydroxy-propyl)adenine
-
 Lupinus luteus
3-Deazaadenine
-
 Lupinus luteus
9-erythro-(2-hydroxyl 3-nonyl)adenine
-
 Lupinus luteus
adenine potent competitive inhibitor, feedback inhibition by one of its products Lupinus luteus
Adenosine 5'-carboxamide
-
 Lupinus luteus
Decoyinine
-
 Lupinus luteus
sinefungin
-
 Lupinus luteus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00031
-
 5'-deoxy-5'-methylthioadenosine
-
 Escherichia coli
0.00041
-
 5'-deoxy-5'-methylthioadenosine
-
 Lupinus luteus
0.00055
-
 5'-methylthioinosine
-
 Lupinus luteus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
31000
-
-
 Escherichia coli
31000
-
 2 * 31000, SDS-PAGE Lupinus luteus
62000
-
-
 Lupinus luteus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-methylthioadenosine + H2O Escherichia coli
-
 ?
-
 ?
5'-methylthioadenosine + H2O Lupinus luteus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Lupinus luteus
-
 yellow lupin
-

Purification (Commentary)

Purification (Comment) Organism
-
 Lupinus luteus

Source Tissue

Source Tissue Comment Organism Textmining
seed
-
 Lupinus luteus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-deoxy-5'-methylthioadenosine + H2O
-
 Escherichia coli 5-methylthio-D-ribose + adenine
-
 ?
5'-deoxy-5'-methylthioadenosine + H2O
-
 Lupinus luteus 5-methylthio-D-ribose + adenine
-
 ?
5'-deoxy-5'-propylthioadenosine + H2O
-
 Lupinus luteus 5-propylthio-D-ribose + adenine
-
 ?
5'-methylthioadenosine + H2O
-
 Escherichia coli ?
-
 ?
5'-methylthioadenosine + H2O
-
 Lupinus luteus ?
-
 ?
5'-methylthioinosine + H2O
-
 Lupinus luteus 5-methylthio-D-ribose + hypoxanthine
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 31000, SDS-PAGE Lupinus luteus

Synonyms

Synonyms Comment Organism
lupin MeSAdo nucleosidase
-
 Lupinus luteus