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Literature summary for 3.2.1.96 extracted from

  • Garbe, J.; Sjoegren, J.; Cosgrave, E.F.; Struwe, W.B.; Bober, M.; Olin, A.I.; Rudd, P.M.; Collin, M.
    EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth (2014), PLoS ONE, 9, e91035.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.96

Protein Variants

Protein Variants Comment Organism
E186Q the mutant has an active beta domain but inactive alpha domain and shows no activity with lactoferrin Enterococcus faecalis
E662Q the mutant has N active alpha domain but inactive beta domain and shows activity towards lactoferrin Enterococcus faecalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-glycosylated immunoglobulin G + H2O Enterococcus faecalis
-
 ?
-
 ?
N-glycosylated immunoglobulin G + H2O Enterococcus faecalis OG1RF
-
 ?
-
 ?
N-glycosylated lactoferrin + H2O Enterococcus faecalis
-
 ?
-
 ?
N-glycosylated lactoferrin + H2O Enterococcus faecalis OG1RF
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis
-
-
-
Enterococcus faecalis OG1RF
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-glycosylated immunoglobulin G + H2O
-
 Enterococcus faecalis ?
-
 ?
N-glycosylated immunoglobulin G + H2O
-
 Enterococcus faecalis OG1RF ?
-
 ?
N-glycosylated lactoferrin + H2O
-
 Enterococcus faecalis ?
-
 ?
N-glycosylated lactoferrin + H2O
-
 Enterococcus faecalis OG1RF ?
-
 ?

Synonyms

Synonyms Comment Organism
endo-beta-N-acetylglucosaminidase
-
 Enterococcus faecalis
endoE
-
 Enterococcus faecalis

General Information

General Information Comment Organism
physiological function endo-beta-N-acetylglucosaminidase EndoE from Enterococcus faecalis hydrolyzes the glycans of the biofilm inhibiting protein lactoferrin and mediates growth Enterococcus faecalis