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Literature summary for 3.2.1.76 extracted from

  • Shapiro, L.J.; Hall, C.W.; Leder, I.G.; Neufeld, E.F.
    The relationship of alpha-L-iduronidase and hurler corrective faktor (1976), Arch. Biochem. Biophys., 172, 156-161.
    View publication on PubMed
Search for more literature for 3.2.1.76

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.31
-
 phenyl alpha-L-iduronide L-iduronidase II Homo sapiens
0.45
-
 phenyl alpha-L-iduronide L-iduronidase I Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
67000
-
 gel filtration, L-iduronidase II Homo sapiens
87000
-
 gel filtration, L-iduronidase I Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein contains glucosamine Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenyl alpha-L-iduronide + H2O
-
 Homo sapiens ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 both forms are stable over 30 min Homo sapiens
65
-
 L-iduronidase II is more labile Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
3 3.5 both forms Homo sapiens