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Literature summary for 3.2.1.62 extracted from

  • Cramm-Behrens, C.I.; Dienst, M.; Jacob, R.
    Apical cargo traverses endosomal compartments on the passage to the cell surface (2008), Traffic, 9, 2206-2220.
    View publication on PubMed
Search for more literature for 3.2.1.62

Activating Compound

Activating Compound Comment Organism Structure
additional information presence of Rab8T22N–CFP results in an increase in LPH–YFP-containing vesicular structures Homo sapiens

Application

Application Comment Organism
additional information regulation of LPH exocytosis by multiple Rab GTPases Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
COS-1 cells triple transfected with LPH–CFP, SI–YFP and Rab4, Rab8 or Rab11 fused to DsRed. MDCK cells stably expressing LPHmyc Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information coexpression with Rab4S22N or Rab11S25N decreases the number of vesicular structures positive for LPH. Trafficking delay of LPH following Rab protein depletion in MDCK cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information sequential passage of LPH through Rab4-, Rab8- and Rab11-containing compartments. Trafficking of LPH from the TGN to the cell surface can be modulated by dominant-negative Rab8 Homo sapiens
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Synonyms

Synonyms Comment Organism
lactase-phlorizin hydrolase
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 Homo sapiens
LPH
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 Homo sapiens