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Literature summary for 3.2.1.62 extracted from
- Phlorizin hydrolase: A beta-glucosidase of hamster intestinal brush border membrane (1969), Biochim. Biophys. Acta, 173, 245-256.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D-galactono-1,4-lactone | competitive inhibition of lactase activity, not phlorizin activity, Ki: 2 mM | Cricetinae |  |
| D-glucono-1,5-lactone | competitive inhibition of phlorizin hydrolysis, Ki: 0.18 mM, competitive inhibition of lactase activity, Ki: 0.275 mM | Cricetinae | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.1 | - |
phlorizin | - |
Cricetinae | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| brush border | - |
Cricetinae | 5903 | - |
| microvillus | - |
Cricetinae | 5902 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phlorizin + H2O | Cricetinae | - |
phloretin + beta-D-glucose | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cricetinae | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | small intestine | Cricetinae | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phlorizin + H2O | - |
Cricetinae | phloretin + beta-D-glucose | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | - |
- |
Cricetinae |
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Release 2023.1 (January 2023)
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