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Literature summary for 3.2.1.52 extracted from

  • Szajda, S.D.; Snarska, J.; Jankowska, A.; Puchalski, Z.; Zwierz, K.
    Isoenzymes A and B of N-acetyl-beta-D-hexosaminidase in serum and urine of patients with pancreatic cancer (2008), Hepatogastroenterology, 55, 695-698.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information concentration and specific activity of total HEX and isoenzyme A are significantly higher in the serum and urine of pancreatic cancer patients in comparison with the concentration and specific activity in the serum and urine of healthy people. Specific activity of isoenzyme B in serum and urine has a tendency to increase in comparison to the control Homo sapiens

Application

Application Comment Organism
medicine activity of HEX and its isoenzyme A determined in the serum and urine can be used as a potential marker of pancreatic adenocarcinoma Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Homo sapiens
-
urine
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl beta-N-acetyl-D-glucosaminide + H2O
-
Homo sapiens 4-nitrophenol + N-acetyl-beta-D-glucosamine
-
?

Synonyms

Synonyms Comment Organism
Hex A
-
Homo sapiens
Hex B
-
Homo sapiens
N-acetyl-beta-D-hexosaminidase
-
Homo sapiens