Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.51 extracted from

  • Liu, T.W.; Ho, C.W.; Huang, H.H.; Chang, S.M.; Popat, S.D.; Wang, Y.T.; Wu, M.S.; Chen, Y.J.; Lin, C.H.
    Role for alpha-L-fucosidase in the control of Helicobacter pylori-infected gastric cancer cells (2009), Proc. Natl. Acad. Sci. USA, 106, 14581-14586.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine gastric cancer cells infected with Helicobacter pylori secrete isoform Fuc2A. Fuc2A is essential for Helicobacter pylori adhesion, in particular to the gastric cancer- and duodenal ulcer-specific strains. FUCA2 significantly enhances the expression of Lewis x antigen in Helicobacter pylori, which is critical for bacterial cell adhesion in the pathogenesis and defense strategy to escape host surveillance Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular gastric cancer cells infected with Helicobacter pylori secrete isoform Fuc2A Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
isoform FucA2
-

Source Tissue

Source Tissue Comment Organism Textmining
carcinoma cell gastric cancer cell. Cells infected with Helicobacter pylori secrete isoform Fuc2A Homo sapiens
-

Synonyms

Synonyms Comment Organism
Fuca2
-
Homo sapiens