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Literature summary for 3.2.1.49 extracted from

  • Greco, M.; Mitri, M.D.; Chiriaco, F.; Leo, G.; Brienza, E.; Maffia, M.
    Serum proteomic profile of cutaneous malignant melanoma and relation to cancer progression: association to tumor derived alpha-N-acetylgalactosaminidase activity (2009), Cancer Lett., 283, 222-229.
    View publication on PubMed
Search for more literature for 3.2.1.49

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular serum enzyme Homo sapiens
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell cutaneous melanoma, specific enzymatic activity of serum alpha-N-acetylgalactosaminidase is significantly increased in stage III melanoma patients, but not in early stages Homo sapiens
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serum specific enzymatic activity of serum alpha-N-acetylgalactosaminidase is significantly increased in stage III melanoma patients, but not in early stages Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl alpha-D-N-acetylgalactosaminide + H2O
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 Homo sapiens 4-nitrophenol + N-acetyl-D-galactosamine
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 ?

Synonyms

Synonyms Comment Organism
NagA
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 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Homo sapiens