Literature summary for 3.2.1.48 extracted from

Simsek, M.; Quezada-Calvillo, R.; Ferruzzi, M.G.; Nichols, B.L.; Hamaker, B.R.
Dietary phenolic compounds selectively inhibit the individual subunits of maltase-glucoamylase and sucrase-isomaltase with the potential of modulating glucose release (2015), J. Agric. Food Chem., 63, 3873-3879 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Drosophila S2 cells	Homo sapiens
expression in Drosophila S2 cells	Mus musculus
recombinant expression in a baculovirus-Sf9 insect cell system	Homo sapiens
recombinant expression in a baculovirus-Sf9 insect cell system	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
(+)-catechin	noncompetitive	Homo sapiens
(+)-catechin	noncompetitive	Mus musculus
(-)-epigallocatechin gallate	noncompetitive	Homo sapiens
(-)-epigallocatechin gallate	noncompetitive	Mus musculus
caffeic acid	noncompetitive	Homo sapiens
caffeic acid	noncompetitive	Mus musculus
chlorogenic acid	noncompetitive	Homo sapiens
chlorogenic acid	noncompetitive	Mus musculus
gallic acid	noncompetitive	Homo sapiens
gallic acid	noncompetitive	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P14410	-	-
Mus musculus	B5THE3	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
maltose + H2O	-	Homo sapiens	alpha-D-glucose + D-glucose	-	?
maltose + H2O	-	Mus musculus	alpha-D-glucose + D-glucose	-	?

Synonyms

Synonyms	Comment	Organism
sucrase-isomaltase	-	Homo sapiens
sucrase-isomaltase	-	Mus musculus

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Release 2023.1 (January 2023)