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Literature summary for 3.2.1.48 extracted from

  • Beaulieu, J.F.; Weiser, M.M.; Herrera, L.; Quaroni, A.
    Detection and characterization of sucrase-isomaltase in adult human colon and in colonic polyps (1990), Gastroenterology, 98, 1467-1477.
    View publication on PubMed

Application

Application Comment Organism
medicine sucrase-isomaltase SI is a marker enzyme of the absorptive villose cells in adult small intestine, human intestinal sucrase-isomaltase help develop a specific inhibitor of sucrase, to retard the absorption of sucrose in the intestinal tract of diabetic patients Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
220000
-
ultracentrifugation analysis, mature complex precursor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
maltose + H2O Homo sapiens
-
2 glucose
-
?
sucrose + H2O Homo sapiens
-
D-glucose + D-fructose
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
sucrase-isomaltase in adult human colon and colonic polyps
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
maltose + H2O
-
Homo sapiens 2 glucose
-
?
sucrose + H2O
-
Homo sapiens D-glucose + D-fructose
-
?

Subunits

Subunits Comment Organism
dimer
-
Homo sapiens