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Literature summary for 3.2.1.48 extracted from
- Sodium-dependent activation of intestinal brush-border sucrase: correlation with activation by deprotonation from pH 5 to 7 (1982), Arch. Biochem. Biophys., 218, 263-274.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| H+ | competitive inhibitor in the interaction of sucrase with sucrose and sodium | Oryctolagus cuniculus |  |
| Li+ | high concentration, 300 mM Li+, pH dependent inhibition, complete at pH 8 | Oryctolagus cuniculus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Na+ | low concentration: activation | Oryctolagus cuniculus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| maltose + H2O | Oryctolagus cuniculus | - |
2 glucose | - |
? | |
| sucrose + H2O | Oryctolagus cuniculus | - |
D-glucose + D-fructose | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryctolagus cuniculus | - |
rabbit | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| maltose + H2O | - |
Oryctolagus cuniculus | 2 glucose | - |
? | |
| sucrose + H2O | - |
Oryctolagus cuniculus | D-glucose + D-fructose | - |
? | |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 17 | 37 | - |
Oryctolagus cuniculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | 7.4 | - |
Oryctolagus cuniculus |
| 4.8 | 9.2 | activating effect of sodium in the pH-range 4.8-7.2 | Oryctolagus cuniculus |
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