Literature summary for 3.2.1.46 extracted from

Luzi, P.; Rafi, M.A.; Victoria, T.; Baskin, G.B.; Wenger, D.A.
Characterization of the rhesus monkey galactocerebrosidase (GALC) cDNA and gene and identification of the mutation causing globoid cell leukodystrophy (Krabbe disease) in this primate (1997), Genomics, 42, 319-324.

Search for more literature for 3.2.1.46

Application

Application	Comment	Organism
medicine	enzyme deficiency in globoid cell leucodystrophy or Krabbe disease	Macaca mulatta

Cloned(Commentary)

Cloned (Comment)	Organism
mutation in Krabbe disease	Macaca mulatta

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-galactosyl-N-acylsphingosine + H2O	Macaca mulatta	-	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Macaca mulatta	O02791	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leukocyte	-	Macaca mulatta	-
skin fibroblast	in culture	Macaca mulatta	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-galactosyl-N-acylsphingosine + H2O	-	Macaca mulatta	D-galactose + N-acylsphingosine	-	?
D-galactosyl-N-acylsphingosine + H2O	-	Macaca mulatta	?	-	?
galactocerebroside + H2O	-	Macaca mulatta	D-galactose + N-acylceramide	-	?
galactosylceramide + H2O	-	Macaca mulatta	D-galactose + N-acylceramide	-	?

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Release 2023.1 (January 2023)