Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-1-C-butyl-1-deoxynojirimycin | - |
Homo sapiens | |
alpha-1-C-hexyl-1-deoxyimino-D-xylitol | - |
Homo sapiens | |
alpha-1-C-hexyl-1-deoxynojirimycin | - |
Homo sapiens | |
alpha-1-C-nonyl-1-deoxyimino-D-xylitol | strong inhibitor | Homo sapiens | |
alpha-1-C-propyl-1-deoxyimino-D-xylitol | - |
Homo sapiens | |
alpha-1-C-propyl-1-deoxynojirimycin | - |
Homo sapiens | |
beta-1-C-butyl-1,5-dideoxy-1,5-imino-L-iditol | - |
Homo sapiens | |
beta-1-C-hexyl-1,5-dideoxy-1,5-imino-L-iditol | - |
Homo sapiens | |
beta-1-C-propyl-1,5-dideoxy-1,5-imino-L-iditol | - |
Homo sapiens | |
additional information | not inhibited by beta-1-C-(2,3-dihydroxypropyl)-1,5-dideoxy-1,5-imino-L-iditol | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucosylceramide + H2O | Homo sapiens | - |
beta-D-glucose + ceramide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl beta-D-glucopyranoside + H2O | - |
Homo sapiens | 4-nitrophenol + D-glucopyranose | - |
? | |
glucosylceramide + H2O | - |
Homo sapiens | beta-D-glucose + ceramide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-glucocerebrosidase | - |
Homo sapiens |
Ceredase | commercial preparation | Homo sapiens |
Gcase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
2.2 | - |
alpha-1-C-nonyl-1-deoxyimino-D-xylitol | in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000019 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | alpha-1-C-hexyl-1-deoxyimino-D-xylitol | |
0.00056 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | alpha-1-C-propyl-1-deoxyimino-D-xylitol | |
0.0042 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | alpha-1-C-hexyl-1-deoxynojirimycin | |
0.043 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | beta-1-C-hexyl-1,5-dideoxy-1,5-imino-L-iditol | |
0.1 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | alpha-1-C-butyl-1-deoxynojirimycin | |
0.147 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | beta-1-C-butyl-1,5-dideoxy-1,5-imino-L-iditol | |
0.4 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | alpha-1-C-propyl-1-deoxynojirimycin | |
0.487 | - |
in 0.15 M citrate-phosphate buffer (pH 5.5), 1% sodium taurocholate/Triton X-100, at 37°C | Homo sapiens | beta-1-C-propyl-1,5-dideoxy-1,5-imino-L-iditol |