Literature summary for 3.2.1.45 extracted from

Bleijlevens, B.; van Breemen, M.J.; Donker-Koopman, W.E.; de Koster, C.G.; Aerts, J.M.
Detection of mutant protein in complex biological samples: glucocerebrosidase mutations in Gauchers disease (2008), Anal. Biochem., 372, 52-61.

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Protein Variants

Protein Variants	Comment	Organism
L444P	mutation results in enzyme with low folding efficacy	Homo sapiens
N370Sr	mutation results in a protein that is largely properly folded and stable but with low specific activity at pH values greater than 5	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
63000	-	SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
PS20 ProteinChip Arrays with the immobilized anti-GC mAb 8E4	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
spleen	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
Cerezyme	-	Homo sapiens
glucocerebrosidase	-	Homo sapiens

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Release 2023.1 (January 2023)