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Literature summary for 3.2.1.45 extracted from

  • Michelakakis, H.; Dimitriou, E.; Van Weely, S.; Boot, R.G.; Mavridou, I.; Verhoek, M.; Aerts, J.M.
    Characterization of glucocerebrosidase in Greek Gaucher disease patients: mutation analysis and biochemical studies (1995), J. Inherit. Metab. Dis., 18, 609-615.
    View publication on PubMed
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Application

Application Comment Organism
medicine
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 normal and Gaucher disease enzyme
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast skin fibroblasts in culture Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Homo sapiens methylumbelliferone + glucose
-
 ?
6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosyl 1-O-beta-D-glucoside + H2O NBD-glucocerebroside Homo sapiens D-glucose + 6(N-methyl-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl))aminohexyl-2-N-sphingosine
-
 ?
glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?