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Literature summary for 3.2.1.45 extracted from
- Functional human saposins expressed in Escherichia coli. Evidence for binding and activation properties of saposins C with acid beta-glucosidase (1994), J. Biol. Chem., 269, 16746-16753.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| saposin-A | - |
Homo sapiens | |
| saposin-C | recombinant and mutant proteins | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glucocerebroside + H2O | Homo sapiens | - |
glucose + ceramide | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl-beta-D-glucopyranoside + H2O | - |
Homo sapiens | methylumbelliferone + glucose | - |
? | |
| glucocerebroside + H2O | - |
Homo sapiens | glucose + ceramide | - |
? | |
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Release 2023.1 (January 2023)
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