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Literature summary for 3.2.1.45 extracted from

  • Daniels, L.B.; Glew, R.H.
    beta-D-Glucosidases in tissue (1984), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 4, 217-226.
No PubMed abstract available
Search for more literature for 3.2.1.45

Activating Compound

Activating Compound Comment Organism Structure
glycoprotein heat-stable Homo sapiens
heat-stable factor
-
 Mus musculus
heat-stable factor
-
 Homo sapiens
heat-stable factor
-
 Rattus norvegicus
sodium taurocholate
-
 Mus musculus
sodium taurocholate
-
 Homo sapiens
sodium taurocholate
-
 Bos taurus
sodium taurodeoxycholate
-
 Homo sapiens

General Stability

General Stability Organism
freezing destroys activity Mus musculus
freezing destroys activity Homo sapiens
freezing destroys activity Rattus norvegicus
freezing destroys activity Sus scrofa
freezing destroys activity Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
-
 Bos taurus
(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
-
 Homo sapiens
(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5
-
 4-methylumbelliferyl-beta-D-glucopyranoside
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Mus musculus 5764
-
lysosome
-
 Homo sapiens 5764
-
lysosome
-
 Rattus norvegicus 5764
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glucocerebroside + H2O Mus musculus
-
 glucose + ceramide
-
 ?
glucocerebroside + H2O Homo sapiens
-
 glucose + ceramide
-
 ?
glucocerebroside + H2O Rattus norvegicus
-
 glucose + ceramide
-
 ?
glucocerebroside + H2O Sus scrofa
-
 glucose + ceramide
-
 ?
glucocerebroside + H2O Bos taurus
-
 glucose + ceramide
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 methods of enzyme determination
-
Homo sapiens
-
 overview
-
Homo sapiens
-
 methods of enzyme determination
-
Mus musculus
-
 methods of enzyme determination
-
Rattus norvegicus
-
 methods of enzyme determination
-
Sus scrofa
-
 methods of enzyme determination
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast skin fibroblasts in culture Homo sapiens
-
monocyte
-
 Homo sapiens
-

Storage Stability

Storage Stability Organism
-43°C, 50% ethylene glycerol, several weeks, no loss of activity Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Mus musculus methylumbelliferone + glucose
-
 ?
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Homo sapiens methylumbelliferone + glucose
-
 ?
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Rattus norvegicus methylumbelliferone + glucose
-
 ?
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Sus scrofa methylumbelliferone + glucose
-
 ?
4-methylumbelliferyl-beta-D-glucopyranoside + H2O
-
 Bos taurus methylumbelliferone + glucose
-
 ?
glucocerebroside + H2O
-
 Mus musculus glucose + ceramide
-
 ?
glucocerebroside + H2O
-
 Homo sapiens glucose + ceramide
-
 ?
glucocerebroside + H2O
-
 Rattus norvegicus glucose + ceramide
-
 ?
glucocerebroside + H2O
-
 Sus scrofa glucose + ceramide
-
 ?
glucocerebroside + H2O
-
 Bos taurus glucose + ceramide
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus
37
-
 assay at Homo sapiens
37
-
 assay at Rattus norvegicus
37
-
 assay at Sus scrofa
37
-
 assay at Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.8 5.8
-
 Homo sapiens
4.8 5.8
-
 Bos taurus