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Literature summary for 3.2.1.35 extracted from
- Identification of a novel chondroitin hydrolase in Caenorhabditis elegans (2008), J. Biol. Chem., 283, 14971-14979.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| 3XFLAG tag | Caenorhabditis elegans |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.12 | - |
chondroitin | apparent KM, substrate calculated as disaccharide | Caenorhabditis elegans |  |
| 0.48 | - |
chondroitin sulfate | apparent KM, substrate calculated as disaccharide | Caenorhabditis elegans | |
| 49.3 | - |
hyaluronic acid from Streptococcus pyogenes (35 kDa) | apparent KM, substrate calculated as disaccharide | Caenorhabditis elegans |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 80000 | - |
SDS-PAGE, presumably glycosylated (53000 Da, expected molecular mass) | Caenorhabditis elegans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
WormBase accession T22C8.2, cDNA: WBGene 00011923 (WormBase) | - |
| Caenorhabditis elegans N2 | - |
WormBase accession T22C8.2, cDNA: WBGene 00011923 (WormBase) | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| chondroitin + H2O | - |
Caenorhabditis elegans | GlcAbeta(1-3)GalNAcbeta(1-4)GlcAbeta(1-3)GalNAc + ? | main product | ir | |
| chondroitin + H2O | - |
Caenorhabditis elegans N2 | GlcAbeta(1-3)GalNAcbeta(1-4)GlcAbeta(1-3)GalNAc + ? | main product | ir | |
| chondroitin sulfate + H2O | - |
Caenorhabditis elegans | ? | - |
? | |
| chondroitin sulfate + H2O | - |
Caenorhabditis elegans N2 | ? | - |
? | |
| hyaluronic acid + H2O | - |
Caenorhabditis elegans | ? | - |
? | |
| hyaluronic acid + H2O | - |
Caenorhabditis elegans N2 | ? | - |
? | |
| hyaluronic acid from Streptococcus pyogenes (35 kDa) + H2O | - |
Caenorhabditis elegans | ? | - |
? | |
| hyaluronic acid from Streptococcus pyogenes (35 kDa) + H2O | - |
Caenorhabditis elegans N2 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hyaluronidase | - |
Caenorhabditis elegans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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