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Literature summary for 3.2.1.28 extracted from
- Functional characterization of Helicoverpa armigera trehalase and investigation of physiological effects caused due to its inhibition by validamycin A formulation (2018), Int. J. Biol. Macromol., 112, 638-647 .
Application
| Application | Comment | Organism |
|---|---|---|
| agriculture | trehalase inhibition is a potential insecticidal strategy. Validamycin A is recommended as a prospective value-added ingredient to commercial bio-pesticide formulations | Helicoverpa armigera |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Helicoverpa armigera |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| validamycin A | validamycin A binds at the active site with multiple hydrogen bonds | Helicoverpa armigera |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.34 | - |
alpha,alpha-trehalose | pH and temperature not specified in the publication | Helicoverpa armigera | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
SDS-PAGE | Helicoverpa armigera |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Helicoverpa armigera | A0A0F6PB63 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Helicoverpa armigera |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha,alpha-trehalose + H2O | - |
Helicoverpa armigera | beta-D-glucose + alpha-D-glucose | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 65000, SDS-PAGE | Helicoverpa armigera |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HaTre-1 | - |
Helicoverpa armigera |
| trehalase-1 | - |
Helicoverpa armigera |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
- |
Helicoverpa armigera |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | 65 | 37°C: about 40% of maximal activity, 65°C: about 70% of maximal activity | Helicoverpa armigera |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Helicoverpa armigera |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000003 | - |
validamycin A | pH and temperature not specified in the publication | Helicoverpa armigera | |
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